Our experienced oncologists and nurses are dedicated to developing innovative treatments designed to improve the lives of people with cancer.
Clinical Trials for Oncology
NHO Revive Clinical Trials for Cancer
Expertly conducting cancer clinical research to make precision medicine accessible to everyone. Our experienced oncologists and research staff in Nebraska bring extensive expertise from clinical and research settings, ensuring top-quality care and the highest standards of scientific data integrity. Explore our clinical trials for Oncology in Nebraska.
Metastatic Breast Cancer
Metastatic breast cancer, also known as stage IV breast cancer, presents a significant oncological challenge with a 5-year relative survival rate of around 27%. This aggressive form of cancer can spread to distant organs, complicating treatment and making the journey particularly difficult for those affected. Survival rates can vary based on factors like the type of metastases and treatment efficacy. In contrast, early detected breast cancer, confined to the breast and nearby lymph nodes, has a 5-year relative survival rate often exceeding 90%.
NHO Revive is acutely aware of the challenges posed by metastatic breast cancer and is actively conducting research to explore potential therapeutic options. Our commitment is to provide exceptional care and unwavering support throughout your participation in our clinical trials for cancer, aiming to improve outcomes and offer hope to those on this journey.
Age
18 Years and older
Gender
Male and Female
Condition
Metastatic Breast Cancer
Current Status
Recruiting
Location
Nebraska
Advanced Solid Tumor
Advanced solid tumors are abnormal masses that typically lack cysts or liquid areas, accounting for approximately 90% of adult cancers. These tumors can be benign or malignant and are classified based on their originating cell type, such as sarcomas, carcinomas, and lymphomas. Unlike solid tumors, leukemias (blood cancers) generally do not form solid masses.
NHO Revive recognizes the challenges posed by advanced solid tumors and is actively conducting research studies to explore potential treatments. Our mission is to provide exceptional care and unwavering support throughout your journey in our clinical trials for cancer.
Age
18 Years and older
Gender
Male and Female
Condition
Solid Tumors
Current Status
Recruiting
Location
Nebraska
Diffuse Large B-Cell Lymphoma
Diffuse Large B-Cell Lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma, accounting for 85% of cases. It results from genetic mutations that transform healthy B-cells into fast-growing cancer cells, which can spread rapidly to lymph nodes and other organs. About 60-70% of patients achieve long-term remission, with prognosis influenced by factors like age, overall health, and disease stage. Early detection and personalized treatment are crucial for better outcomes. Some cases resist standard treatments, prompting researchers to explore alternative therapies.
At NHO Revive, we are committed to developing new treatments for DLBCL through innovative clinical trials. Our clinical trial for cancer focuses on creating novel drugs that target the underlying mechanisms of the disease, aiming to improve patient outcomes and offer new hope in the fight against this aggressive cancer.
Age
18 –79 Years
Gender
Male and Female
Condition
DLBCL
Current Status
Recruiting
Location
Nebraska
Refractory Multiple Myeloma
Refractory multiple myeloma is a type of blood cancer that begins in plasma cells, a kind of white blood cell in the bone marrow. These malignant plasma cells can accumulate, forming tumors in bones such as the spine, skull, pelvis, and ribs. The disease can progress rapidly, causing symptoms like bone pain, fractures, anemia, and kidney dysfunction.
NHO Revive is conducting clinical trials for cancer to evaluate an investigational drug for refractory multiple myeloma, comparing its efficacy to existing treatments. This research aims to determine the drug’s effectiveness and safety, potentially offering improved treatment options for patients with this form of cancer. By participating in clinical trials for oncology, patients can contribute to advancements in multiple myeloma therapy and access new, potentially more effective treatments.
Age
18 –79 Years
Gender
Male and Female
Condition
Multiple Myeloma
Current Status
Not Recruiting
Location
Nebraska
Myelofibrosis
Myelofibrosis is a rare bone marrow cancer that disrupts normal blood cell production, affecting 1 to 9 in every 100,000 people. This condition causes significant scarring in the bone marrow, leading to severe anemia, which results in weakness and fatigue. The scarring also reduces platelet numbers, increasing bleeding risk, and often causes an enlarged spleen. Myelofibrosis can occur independently (primary) or develop from another bone marrow disorder (secondary).
NHO Revive’s myelofibrosis clinical trial for cancer aims to investigate the safety and efficacy of an investigational drug with the potential to effectively target this cancer. Our commitment is to bring innovative treatments to patients, enhancing their well-being and quality of life.
Age
≥ 18 years
Gender
Male and Female
Condition
Myelofibrosis
Current Status
Not Recruiting
Location
Nebraska
Non-Small Cell Lung Cancer
Cancer occurs when cells in a specific part of the body reproduce uncontrollably. Non-small cell lung cancer (NSCLC) forms cancerous cells in lung tissues. Our clinical trials for cancer aim to compare the effectiveness and safety of investigational drugs in adult participants against current lung cancer treatments. This study will assess changes in disease activity and associated effects.
Although NSCLC spreads more slowly than small cell lung cancer, it still presents significant challenges and is a leading cause of cancer-related mortality worldwide. Participants in our trials must attend regular hospital visits for check-ups, blood tests, side effect monitoring, and complete questionnaires. Clinical trials for cancer are essential to evaluate the treatment’s impact and ensure comprehensive care.
Age
18 years and older
Gender
Male and Female
Condition
NSCLC
Current Status
Recruiting
Location
Nebraska
Diffuse Large B-cell Lymphoma and Classic Follicular Lymphoma
B-cell lymphoma is an aggressive cancer that targets the white blood cells responsible for fighting infections. Classic lymphoma typically grows slowly and gradually, classified as a form of non-Hodgkin lymphoma. Our follicular lymphoma clinical trials for cancer aim to evaluate the safety and efficacy of an investigational drug in individuals with relapsed or refractory diffuse large B-cell lymphoma.
Participants must have follicular lymphoma and have received at least one prior systemic therapy. These clinical trials for oncology involve a higher treatment burden than standard therapies. To monitor the investigational drug’s effects, participants will undergo regular medical assessments at an approved institution, ensuring comprehensive evaluation and safety monitoring throughout the study.
Age
18 years and older
Gender
Male and Female
Condition
Diffuse Large B-cell Lymphoma and Classic Follicular Lymphoma
Current Status
Not Recruiting
Location
Nebraska
Early Breast Cancer
Early-stage breast cancer occurs when cells in the breast mutate, causing them to proliferate and form tumors. Early-stage breast cancer is localized within the breast or nearby axillary lymph nodes. This phase 3 open-label study aims to evaluate whether the investigational drug provides better outcomes compared to standard therapy for patients.
The study targets patients with early-stage breast cancer who are at intermediate-high or high risk of recurrence after initial therapy. Eligible participants must meet specific criteria to enroll. The study will track patient outcomes for up to 10 years, with a treatment duration of 7 years for each arm, to thoroughly assess the long-term efficacy and safety of the investigational drug through these clinical trials for cancer.
Age
18 years and older
Gender
Male and Female
Condition
Early Breast Cancer
Current Status
Recruiting
Location
Nebraska
Chronic Myelogenous Leukemia
Chronic myelogenous leukemia (CML) is a cancer originating in the blood-forming cells of the bone marrow, leading to uncontrolled growth of abnormal white blood cells due to DNA changes. This CML research study spans three phases to evaluate the efficacy of the investigational drug. Patients will be screened for specific mutations and excluded if such mutations are detected.
These clinical trials aim to discover new, effective treatments for patients with bone marrow cancer. Our clinical trials for cancer involve a comprehensive assessment of the investigational drug to ensure its efficacy and safety in treating CML. By participating, patients contribute to advancing potential treatments and improving outcomes for those affected by this type of cancer.
Age
18 years and older
Gender
Male and Female
Condition
Chronic Myelogenous Leukemia
Current Status
Recruiting
Location
Nebraska
Frequently Asked Questions
Want to know more about our clinical trials for cancer? Here are some frequently asked questions that provide you with a deeper understanding of this crucial field.
How can I join a clinical trial?
Talk to your doctor or search online databases like ClinicalTrials.gov for relevant studies.
Why is clinical research important?
It develops new treatments, improves existing ones, and helps us understand diseases better.
What are the phases of a clinical trial?
Phases 1-3 test safety, effectiveness, and comparison to current treatments. Phase 4 monitors after approval.
Are clinical trials safe?
Yes, they have strict protocols, informed consent, IRB oversight, and allow you to withdraw at any time.
Can I leave a clinical trial after it starts?
Answer: Absolutely. Participation is voluntary, and you can choose to withdraw for any reason.
What is an investigational drug?
It’s a medication or treatment still under development being tested for safety and effectiveness in clinical trials for cancer.